edit: "isn't this implemented in-browser?" comments: maybe, but it's to the browser's implementation. These plugins are reviewable separate from their analogous browser implementation.
Isn’t NoScript redundant if you run UBO in medium mode?
Roughly similar to using Adblock Plus with many filter lists + NoScript with 1st-party scripts/frames automatically trusted. Unlike NoScript however, you can easily point-and-click to block/allow scripts on a per-site basis.
If you go in ublock origin settings, scroll all the way down, you can toggle a setting that disables JS by default. On each site you can whitelist it by clicking ubo and enable JS.