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Right now it's pretty much just HDR and music production softwares that don't run on Linux.
Reaper runs on Linux
True. However Most of the plugins I use don't.
Also, I'm an FL Studio guy though learning reaper wouldn't be out of the question if my plugins worked.
Have you checked out ardour?
Multiplayer (competitive?) gaming in general is pretty poorly supported on Linux. It's not necessarily Linux's fault: it's enough to deal with one OS's loopholes as an anti cheat developer, let alone two or more; but if you happen to actually enjoy playing games like Valorant, League of Legends, PUBG, Counter Strike or basically most of the big names, then, unfortunately, you don't really have a choice.
I've been waiting for the (nearly?) full compatibility of multiplayer games for 20 years. I would love to solely use Linux, but I'm afraid it's not just HDR or music production.
Some desktop environments (plasma 6 at least) support it when running in Wayland - my daily driver for months has been an HDR setup (with a nvidia gpu, even) and it’s been great. It’s not quite ready for non-technical users, but imo it’s not far off and I can’t wait for it to be more common.
I think we just need more options for creative software