I understood the terminology but after googling still don't get the meme. The only results I can find are about how paracetamol during pregnancy may increase likelihood of autism - nothing about how it affects autistic people differently than neurotypicals. Hopefully OP can clarify, because I'd love to learn more.
For me, paracetamol/tylenol/acetaminophen helps me significantly when I feel overwhelmed and went over my limit. It suppresses a lot of stuff related to sensitivity and can also help me last longer if there's an important event I need to be at for some reason or another.
Other people I've talked to just say paracetamol make them tired, hence they sell them in combination with caffeïne I'm guessing.
The caffeine is usually added to make it faster acting, particularly for migraines. I haven't actually heard of it making anyone sleepy before, that's interesting.