Pirated apps are one of the top source for botnet operators to infect new machines and add them to their network. Try not to run any pirated app or game if you can, but if you can't avoid it, get it from trusted sources (e.g. directly from the cracker's homepage), not from random sources like TPB where anyone can upload anything.
It's generally safe, but doesn't mean it's bulletproof as sites has been removed from the megathread in the past when they suddenly serve malwares or miners. Just use your common sense when downloading apps and games and scan them before installing.
thank you, don't pirated games always trigger antimalware software (if so, isn't it pointless to scan them)? Forgive me I've not been pirating much for the past 10 years.
The scanners should tell you the reason they flag a file. If it's marked as trojan, obviously don't run it. Cracks are usually marked as crack by most antivirus.
You can also upload the flagged files to virustotal to see what other antiviruses flag the files for.