@nuclide has setup their Linux desktop in the most Lispy way possible: #GuileScheme bindings in order to program the #Wayland compositor (DWL) and the status bar (DTao), #Nyxt for the web browser (#CommonLisp bindings to #webkit ) and #Emacs as the text editor.
The only way you could be more truly a #Lisp fan is if you ran an emulator of the CADR Lisp Machine and used ZMacs as your text editor instead, and annoyingly argue with everyone that Scheme is not actually Lisp (cough @amszmidt cough)