Should UI frameworks have separate files for UI and application code?

Do you prefer to use UI frameworks which make a distinction between UI files and application code (e.g. Qt, GTK, Angular) or do you prefer to define the UI in the application code (e.g. Flutter, Jetpack Compose, React)?

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I did both, separated is my way to go. Having both separated makes things easier and cleaner IMHO. You can have a designer to create these seperated layouts, which is pretty cool when you're a UI/UX designer. The ability to reuse the same code with a different UI layout. And of course generates less conflicts on Git when someone worked on the code while you where on the UI.