A disease that makes crops inedible would be so much worse than any pandemic
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I meanbstuff like that exists, ergot for example really sucks. But you can kill and burn infected plants and animals. Can`t really do that with humans. So it is overall much easier to controll.
Edit: Some weird formating stuff
Ergot was what i was going to reply with
there is asso things like potato blight that in part caused the Great Famine