While previously you've been able to play League of Legends on Linux, and there's some pretty die-hard fans using Wine to play it, that's set to end soon with Vanguard being introduced.
This also applies to Valorant. I know a lot of people look down on both games, but it's still unfortunate for Linux to lose access to such a popular game.
I thought this part was particularly interesting:
Half of anti-cheat is making sure the environment hasn't been tampered with, and this is extremely hard on Linux by design. Any backdoors we leave open for it are ones [cheat] developers will immediately leverage for cheats