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What if instead of viruses or diseases killing you it was your brains increasingly escalatory responses to the virus. Basically the braining saying I'm killing this thing or I'm gonna die trying. I dont the science behind it but I'm high as.
You're basically describing an allergic reaction.
There are many, many diseases caused by your own immune system attacking your body. The brain itself cannot "attack" anything unless you count seizures and the like. Maybe several forms of psychosis could fit the bill with even more stretching, but there is little your brain can do outside of interfering with bodily functions. If you seizure that hard outside of a hospital bed, you're probably SOL in most cases.
Lupus has entered the chat
It's never House.
Great description of Ebola.