I am in the process of setting up a home server, and I am struggling to decide. I have previously used yunohost but in the meantime, freedom box has matured quite a bit. I have also looked at Tipi.
The use case right now is, running a wireguard server and probably some notes of sorts (to be decided). A web GUI for management and updating would be much desired.
Disclaimer: I don't have too much surplus of energy, due to a hectic life, so I would prefer something easy and without the requirement of docker/kubernettes
I highly recommend using Docker/Podman, even though you say you don't want to. It is trivial to start up a new service using docker-compose once you get the basics down.
host:container when specifying ports or directories in the compose YAML (e.g. 58333:8080 will route the container's port 8080 to the host machine's port 58333.