Would a vacuum extraction affect a QWISO solution?

Basically title. If I make a quick wash isopropyl alcohol (QWISO) solution, would a vacuum extraction have a meaningful effect on the resulting concentrate? I'm doubt it would have a meaningful impact in terms of flavor and terpene content, but I can see it producing an interesting consistency. The only way I could see it affecting flavor would be if the low pressure caused some volatiles to change, but I kinda doubt that. For the vacuum extraction I would probably just put it in a vacuum chamber.