I've been using Raspbian and Lakka on some SBCs. But I'm not sure what distros to take the plunge with on my desktop running Intel 9th Gen and 2080 ti.
I'm really liking Pop!_OS, but I am far from an expert. Big draw to me is that is very unWIndowslike as far as UI go. And the auto tiling is slick, but you can implement that on pretty much any distro I believe. I tried EndeavourOS as well, but since it's Arch based it was a bit too different than what I'm used to. I have two VPS running Ubuntu 20.04 LTS and since Pop is Ubuntu based it was more familiar. Pop also has a Nvidia specific image.
The new Debian-based Mint looks neat as well, but for now I'm very content with Pop.
Nothing unique about the release, proton gets better and better. There are some games however that will likely never work, because their studio or developer blocks it. Most of these are competitive shooters. As long as you are OK not playing these, any time is a good time.