'Universal cancer vaccine' trains the immune system to kill any tumor
'Universal cancer vaccine' trains the immune system to kill any tumor
newatlas.com
'Universal cancer vaccine' trains the immune system to kill any tumor
113 comments
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Too bad we got a Sociopathic Oligarchs as HSS, who thinks mRNA vaccines should be banned. Cancer is better than...well, whatever is wrong with mRNA vaccines.
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I'll read the publication in the coming days and report back, but don't get your hopes up. There's a "breakthrough" in cancer research every few months and it leads to nothing. And this study was done in mice which are a bit different to humans (citation needed)
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They cured hair loss in mice at least twenty times now and we still have bald humans
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They should probably find a way to turn humans into mice. It's a shame to leave billions of dollars on the table like that.
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Why do we not simply transplant the hair from the mice, onto the humans?
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"Mice lie and monkeys exaggerate."
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That's cause they're not on dutasteride, finasteride, or estrogen therapy. It's all the fault of DHT.
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We have hair loss cures for humans too, the main roadblock for use is men like functioning balls.
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I think this is overly negative. There have been multiple significant advances in cancer treatment over the past 10 years. It just depends which type you get.
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Maybe overly negative by saying they come to "nothing", but if you trace those advances back to their initial press release stage, they generally way ovehype it.
Here we have what is being heralded as maybe a universal response to any and all cancer. That would be a shockingly amazing deviation from basically all the cancer research to date. It's possible and wonderful if true, but generally the research falls short of the initial press coverage, even if it amounts to something.
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while you're not wrong i do want to reiterate that mRNA vaccines are likely going to be how we treat and cure cancers so there is precedent at least for this to be massive news. if not this there will likely be a real announcement one day.
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The likelihood that all cancers express a common surface marker that is never expressed by any non-cancerous cell seems pretty low. Not a cancer biologist, but there's all kind of different genetic paths to cancer - why would they all cause some specific molecule to be expressed and why would no other cell ever use it?
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Eh a lot of them save some lives. Its just cancer is really good at killing people and there are a lot of types of cancer
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It's why I start following it myself when it gets to the human trial stage and less the breakthrough stage. There, you make the assumption that they have a plan and are much more confident in the product.
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I will remain eternally hopeful! Maybe someday. Maybe!
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How about fusion power and room temperature superconductors...
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Rfk is about to wake up and fire everyone doing this research.
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When we say "healthcare" we mean caring for the health of healthcare corporations.
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Hopefully, the researchers will be fully employed by the EU. I wouldn't trust the US to not fuck up this miracle.
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“How much would you pay to not die of a tumour?”
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I'm gonna be watching with popcorn when anti-vaxxers get cancer and definitely 100% will take this vaccine.
I mean, if it's true and not just shit science reporting that I assume it is.
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Previous research has focused more on homing in on a target or tailoring a vaccine specific to a patient's own cancer profile.
"This study suggests a third emerging paradigm," said study co-author Duane Mitchell, MD. "What we found is by using a vaccine designed not to target cancer specifically but rather to stimulate a strong immunologic response, we could elicit a very strong anticancer reaction. And so this has significant potential to be broadly used across cancer patients – even possibly leading us to an off-the-shelf cancer vaccine."
So... Kinda triggering your own auto-inmune response. But I'd be wary of trouble with overtly aggressive auto-inmune responses, as we already have quite a few diseases coming from these, as well.
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I guess if I was gonna die and absolutely wanted more time I would make the trade off for living with lupus
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living with lupus
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As someone with an autoimmune disorder, I'm honestly not all that sold on whether that's a good tradeoff.
Yay, you're not acutely dying of cancer, but now your body is attacking your internal organs and depending on how shitty your luck is, you can eg. look forward to liver and/or kidney transplants (possibly more than once, too)
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It's never lupus.
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Multiple Sclerosis comes to mind
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Superbugs are gonna look like regular bugs.
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Immune checkpoint inhibitors are already a relatively common therapy for several types of cancer.
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This sounds like the intro plot to one of those zombie movies...
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Because Hollywood is so insanely bad at portraying science even remotely accurately, literally everything sounds like the plot to a zombie movie.
I'm not even kidding, I'm not in the biotech field and even I feel my eye twitch every time I see a movie with zombified lab animals smacking into the bars of their cages as the plucky heroes try to unravel what vile sins against nature those evil researchers uncovered in their hubris.
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Yeah i've had RA since i was 12, that explaination of function just made my brain screech
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amazing. i can already hear the anti vax crowd seething lol
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Conservatives will somehow find a way to level this as devil worshiping blasphemy and let their children die of brain cancer instead.
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What is the catch?
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We'll find out in 30 years
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I can't want to never hear about this again
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This is how I Am Legend starts.
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Win/win I love people that slap Chris Rock
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What? Why?
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Any cancer? How does this work with people who have gene mutations that suppress cancer-fighting defence systems.
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E X T E R M I N A T E/s
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While the formulation isn't unlike the Covid-19 vaccine, which uses lipid nanoparticles to deliver the genetic instructions to the body, it is still somewhat different. Instead of the drug encoding a virus protein, it sends a message to the immune system to rally the troops. It essentially tells the body to produce certain proteins that stimulate the immune system – including a protein within cancer cells known as PD-L1 (Programmed Death-Ligand 1), which makes tumors become more visible to immune cells.
TLDR: they are finding that it’s more effective to make cancer more visible and have the body’s immune system do its thing.
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In this study on mice...
Took them 7 paragraphs to get around to mentioning that.
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But this was based on their treatment of glioblastoma working in humans, and is a modified version of that one.
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CIA hitmen:
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I want to believe.
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Republicans "universal? Not on my watch"
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Universal as in "anyone can pay big $$$ for it"
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mRNA vaccine research in America? don’t need that, cancel the funding!
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Universal Cancer Vaccine? WASTE OF MONEY, CUT IT!
-The Trump Administration!
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"It's not a tumor!!!!"
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I was recently in a conference about synthetic biological approaches to deal with cancer. The only quote I wrote down was "this approach kills cancer in a petri dish, but so does a shotgun"
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All that time thinking it was a funny inside joke in the biological community and someone ripped it off an xkcd. Of course they did. That's hilarious.
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But won’t the thimerosal in the cancer vaccine give everyone autism? Cancer is better than autism!
/s (duh)
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Curing (or at least improving our treatments for) cancer would be great. There's a small part of me that absolutely does not want to see it happen within the next few years because of the current administration. It'd still be an overwhelmingly good thing to accomplish but I dread the future arguments over the time Dr. Don and Bobby got together in the lab to cure cancer through the power of Jesus, bootstraps and grit.
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Sweet baby Jesus, is this it? Is this finally the cure for cancer that everyone's been waiting for?
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My bet this one does cure cancer but makes your immune system too reactive in turn behave like how COVID kills people.
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Sounds great, but don't get excited, it's not for you. It will be priced so that poorz can't afford it, like 5-15 mil a pop
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laughs in european
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Biologically, this argument makes no sense, it's almost certainly written by somebody not familiar with physiology and just trying to sound poetic. That or a journalists severely misinterpreting a quote or analogy from a researcher, which also happens quite a lot.
Cancers have a gigantic variety of causes, but a purposeful signaling pathway is not one.
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What a load of bollocks. Natural cell mutation causes both evolution as well as unwanted side effects, of which cancerous cells are one.
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Every cancer and every body is different. Why search for universal cancer vaccine insted for AI tha will analyze individual biopsy and persons blood work and came up with targetet 100 % efficient cure?
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You need to let the scientists know this! I’m sure your insights will be very valuable to them.
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I'm sure mainstream science will deny it's true, you know how hung up they are on their glass beakers and flasks with colored water. Fukkin glass flask with colored water industry is keeping the truth buried. DOWN WITH BIG GLASS FLASK FULL OF COLORED WATER.
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Why have we been funding researchers when the true answers have been out there on the internet, where we train our valued AI partners? See, AI could have told us we should look to AI for all the solutions! But it needs genius randos on the internet to give them these insights to train on.
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I'd rather go to a literal butcher and ask them to use the cleaver and hope for the best, before i let any fucking tech bro asshole billionaire mess with my body
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He has a point though. In medicine AI actually has its uses, like spotting cancers better than humans can, decoding proteins, and solving protein folding problems.
We're of course talking about AI in the same way any scientist uses a computer, not replacing humans with a glorified text processor.
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Why search for universal cancer vaccine insted for AI
The sign over 7329 Silicon Valley startups hoping to get get bought out by OpenAI or Elon Musk right now.
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113 comments
I read that as: Will never reach the market because it threatens a multibillion dollar industry.
But srsly, glioblastoma is a really nasty motherfucker with a very low patient survival rate, so if they've really managed to cure it that's a huge milestone.