I've been on a Binding of Isaac binge. I thought that I had my fill with it over the years but the deck has really put a new life into it. It's a perfect fit. And I am finding myself playing it again even on the desktop. I thought that I wasn't gonna need Repentence but I guess I will have to get it now.
What control layout are you using? I tried to install this a while back (maybe a year ago?) And at the time the control layouts I found were horrible and made it no fun to play.
I was used to the standard layout from playing on the desktop so I didn't even bother to look at alternatives: move with left stick, shoot with buttons, activate items with triggers and bumpers.
I am curious which part are you unhappy with. Should be easy to customize.