Max weight load for commercial vehicles is actually 20k lbs more, at 80k total.
And the drivers are trained, and most of them do well most of the time.
But some companies run them like Amazon drivers... No matter what happens (brake problems, engine problems, stuck, accident traffic, etc you better get there by X time. That's not such a problem until drivers start driving through their mandatory sleep times to stay awake.
A bit before COVID they implemented an electronic tracker that reports any driving at all during mandated off-times (for sleep).
Before that you'd have truckers either fighting sleep, or, stimulants were a big thing at truck stops, right up there with lot lizards.
I had a girlfriend who's dad was a long-haul trucker. I've heard some seriously fucked and sad stories. Thankfully there have been new safety implementations