Moto Edge 50 Ultra unveiled with SD 8s Gen 3, 64MP 3x periscope and real wood back

A hands-on article from the same website says it's not pure wood. It's been treated to protect it from water and skin oil

The backplate would be the only one made out of wood. It should also have some form of coating to make sure it doesn't get damaged easily. But, prolonged use can damage it like any other smartphone or perhaps more.

Unless, you plan on submerging or washing it on a daily basis. It should be fine.