For many, the idea of having a few dozen hookworms set up shop in your gut sounds more like a Survivor challenge than a beneficial health therapy, but scientists see a bright future in this human worm farm for treating many chronic conditions.
The Parasitology series by Mira Grant is about a future where GMO tapeworms exist in everybody, and are used to take care of all our medical issues. Really interesting concept and read
“The JCU trial provides sufficient proof of concept that infection with live hookworms is safe and appears to have some sort of beneficial effects on people’s metabolic health, which will hopefully be confirmed by future clinical trials designed to confirm efficacy and explore how hookworms influence metabolism,” said Dr Paul Giacomin, AITHM Senior Research Fellow and immunologist.
Eat less vs feed a crop of worms in my guts…. Hmmmmm. I mean, it’s an efficient way of making sure you don’t absorb all the calories you consume. It would be a bummer if my worms’ eggs were infecting people who didn’t over-eat and would be harmed.
The anti-inflammatory aspect is intriguing, but there has to be better options for creating that response.
This “give you worms so you can continue to overeat without consequences” approach is far too reminiscent of the ancient Roman vomitoria. There has to be a less wasteful way to deal with obesity and its metabolic consequences.
The difference between medicine and poison is the dose. The worms were not dangerous at the dose being studied, as indicated by the fact people got healthier over a 2 year period.
I sustained myself for 6 months on nothing but being a medical Guinea pig. Because of anonymity laws they couldn’t ask for documentation so it was one of the few gigs I could do without a work permit. I would have loved this experiment, sure as hell beat the “let’s inject pepper under your skin and give you the placebo painkiller” trial I did for three painful weeks (paid $2800 though).
satan! I read it looking to see how they modified the hookworms and I can't find anything outside of saying they were farmed and lab grown. We do so much de-worming with animals and now im wondering if that is bad for them???
De-worming animals is probably still for the best. Even hookworms can be fatal to dogs, for example. And there are other worm parasites way worse than hookworms, like roundworms that can burrow through the intestines and up into the host's heart and brain. I wouldn't take the risk.
yeah I was just musing and reading the whole paper the participants had some initial gastro intestinal issues for a day or so from getting the worms. seems its basically a very small dose of them can be beneficial so you totally don't want to get them naturally.
So it is, fixed. There is lot of celiac treatments in the pipeline, don't know how close any are to market. Bloody hate it to be honest. Not because there is any gluten food I want, but because of constant having to worry about cross containmination.
It makes sense. Having worms has been a constant across human history, so if we need to bring dirt back to prevent allergies maybe we should all have these guys too.