It was posted about 20 minutes after I finished making it last night. It's based on an older soup alignment chart I remembered coming across. Also I think Twitter is pretty intuitive to use. Open the app, the content is there. Scroll for more, like and retweet what you want to see more of. The app has obviously gone to shit lately but it's still the best example that came to mind for that cell. This comment is not an endorsement of the current state of Twitter.
For me it's the way that replies are shown before what they are replying to, or sometimes after. I feel like every time I saw a Twitter screenshot on Reddit, I had to spend just an extra second to realise the order. I know it's ok once you learn it, but I would definitely not call it the poster child for intuitive design.
If you're talking about quote tweets then I know what you mean. The order was confusing at first for me too but it's been so long I forgot that was even a learning curve I went through.