Hi there,
I was intrigued by the idea of self-hosting my social media accounts, but was more or less a complete noob with all things hosting.
However, with the help of the community here (and quite a few hours spent on it) I finally have a working setup! Mastodon, Matrix, Lemmy, Nextcloud all self-hosted behind Nginx Proxy Manager.
Google can find a lot of answers, but sometimes some really specific input is needed - which you guys have provided over the last couple of weeks - so I just wanna say thank you for that!
It's pretty solid for 1:1 calls, and they are currently working on Matrix's own conferencing protocol/solution.
But until then you could set up a Jitsi Meet instance along with Matrix to run multiple user calls.