I don't think that this cartoon was an intentional reference to crack. (Sadly - that's a great punchline.) The date on the cartoon is 1980, which would have been marginally too early for crack to exist. It certainly wouldn't have been an idea that was floating around mainstream culture.
It's just Larson being a master of weird, non-sequitur humor. And in this case, foretelling the future of underworld transactions in the 80s. Maybe not all psychics are quacks after all.