Massive Ground planes on a multi layer board were my breaking point.
I tried to clean the through holes where a micro USB port was secured and only could get it cleared by drilling out the solder.... (Only had a soldering iron and wick available)
I've done the rgb mod for an old NES. The PPU is on a big ground plane and just impossible to get off using a wick. Or you can, but now you've put so much heat into the chip that you fried it. Need a heat gun or hot plate.
Playstation SD card mod is easier than hand desoldering the NES PPU, and it involves scraping away very thin traces and soldering to them.