"... pedals like Strymon Iridium, Walrus ACS-1, and the new TC Electronic Ampworx lines all do DI too."

In fact, the Strymon Iridium is ONLY for DI, there's no output suitable for plugging into an amp - it's a line-level signal. The manual specifically says not to connect it to a guitar amp.

This to me is its strength! I already have amps, but if I can avoid hauling an amp to a gig or micing an amp if I'm recording, it's a win for me. My tone is more consistent than with a miced amp and sound engineers always seem happier when I just ask for a place to plug in rather than needing a mic.

I've been very happy with the tones I've gotten from the Iridium, to the point where I barely miss an amp, and that's mostly because I don't have a nice spring reverb. Once I get a reverb pedal I'm happy with, I'll likely sell two of my 4 amps.