In all likelihood, the fediverse will not take off like people think it will. It's just slightly too complicated for the average person to instantly give a chance. I don't see any real reason to bring it up in an article like this.

I've been posed the same question about 'if you could only listen to one band' and I usually decide that if I were restricted to just one, I'd sooner drop the hobby altogether. Anything loses its luster after too much repetition for me.

But for the sake of actually answering the question, would have to be something that can't just be shut down, has variety in and of itself, and stands the test of time. So maybe something along the lines of Fallout 4? I know Skyrim is the darling but Fallout 4 has more actual stuff to fiddle with between base building, constant procedural questing, etc. I dunno. That's not a perfect answer, but it's in the same realm at least.