What is our guaranteed tear jerker movie or scene?

What movie or scene from a movie (or show) makes your eyes misty?

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Birdman (with Michael Keaton) - nothing in the actual movie but the absolute soul crushing sadness when I realized that they weren't making a Harvey Birdman Attorney at Law movie.
- You want a tearjerking Michael Keaton movie, watch My Life. Hydrate afterwards, plenty of electrolytes, you're welcome.

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