Can't believe it's not in here yet, but Monster Hunter. I find the eventual understanding of the gameplay loop to not actually be as complex as I thought it'd be, but getting a good overview of all what you want to do and use isn't really possible even in the latest entries, just specific information about specific mechanics.
I couldn't get into MHW at all, and I lay the blame on the awful tutorial, which is less a tutorial and more interrupting you as you try to get to grips with the controls, with dozens of full screen pages of text.
Oh yes, legendarily awful. And again, I don't find it that impenetrable in the end, the delivery of the info is just so bad. If anybody wants to get into MH I'd love to help because I absolutely love the series now, but it took concentrated effort to teach myself without anyone to guide me.