What they seldom or never mention in the Trek universe is the number of dead, wounded, maimed, disfigured, decapitated, dismembered, disemboweled, misconfigured, unconfigured, undone, well done, rearranged, decompiled and disintegrated people and animals it took to perfect the technologies they use safely on a daily basis.
I'm definitely not going to get my body anywhere near any new technology that might even remotely affect my physiology.