I think that's the right take. The original movies had the straight guy, goofy guy, deadpan guy, and regular guy. You could get the wrong energy from an new all male cast too, like casting Chris Farley, David Spade, Adam Sandler, and Martin Lawrance together - it would be just too much of the same kind of comedic vibe.
I was trying to come up with an actual example of "It'd be like if you cast 'x' in 'y' when they're better suited for 'z'" but couldn't come up with an example that truly fit what I was trying to convey.
But that's pretty much what I was going for. They're hilarious all in their own right but it's the wrong type of comedy for Ghostbusters.