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Stocking up makes no sense in Factorio, it's more about a steady flow of resources, keeping up with the demand. The stock will mean nothing if you can't keep it up. You should keep a small buffer to compensate for fluctuations, but anything above that is actually just a frozen asset, that could be used more effectively elsewhere. I don't want to be rude, just wanted to point that out. Have a good day fellow Engineer!
Lol, I know. Just want to make a joke about way too many shiny green rocks.
Ok, I can sleep peacefully then 🥰
Building on this good advice, the appropriate size of that "small buffer" is a function of your usage rate and of how quickly you can respond to incidents: When your Uranium patch runs dry, how quickly can you tap another one, and how much nuclear fuel will be used from your buffer in that time?