Tip: You can bypass Twitch ads on Firefox thanks to Picture-in-Picture
Happened to discover this a while ago.
If an ad starts playing in the main window that moves the livestream to a small window in the top right corner, do the following:
Mute the main stream.
Hover your mouse over to the tiny window and click the PiP button.
Unmute the PiP stream
You can now continue to watch the livestream uninterrupted. Once the ad concludes, the PiP pop-up window automatically closes and the main stream continues.
I usually enlarge the PiP window and move it over the ad to cover it.
Same only solution I have found is a VPN called windscribe I pay for it as it's my VPN of choice right now and increadblt cheap but anyways it has a browser ad on that you can turn on then put in a region (I forgot what one) because apparently twitch can not show ads there. It has worked for me I don't watch much twitch anymore but when I do it seems to work.
It's a regional thing. From time to time, ublock origin fails but it'll work again after the filter lists are updated. Even if it works, the stream will stop and you have to reload the page.
Whattttt!? I mean I guess that makes sense. I will have to try this. Usually I watch twitch via Chromecast on my tv. For whatever reason no ads play when doing that.