I have always wanted to try printing larger, using a bigger nozzle - just got around to swapping to a .6mm in my MK3S+. Printed a gift for a childhood friend. 300% size. Took just under 10 hrs. With the slicer settings on .4mm it was over 17hrs.
When it works, it's pretty great. I've got a weird overextrusion issue to fix on my MK3S+ with the 0.6 nozzle, but the prints themselves are tougher and faster.
Thanks for the ideas, yeah I've tried playing around with the presets and such, and I'm fairly certain the filament itself is good, matterhackers pro PETG.
When I have a moment I'll be trying to make an extrusion tower to test settings.