Pihole will also block non-browser traffic (e.g. your OS phoning home). Adblocking extensions are typically restricted to just blocking traffic of the browser it’s installed on.
It also operates on your entire home network, so it can block junk traffic on devices that can’t run adblockers.
uBlock Origin at a minimum. But I would suggest a privacy focused browser. Librewolf, Mulvad or even Brave. Browsers leak
so much information about you it is easy for sites to fingerprint and track you even with an ad blocker.
I know Librewolf is working on their DNS leakage (last section on privacytests.org), but they also allow you to select a privacy focused DNS server which is nice when you’re not on a network you own, so you can’t run PiHole.