I still haven't played PoE2, and I completed PoE1 twice. Something about the character creation in PoE doesn't quite hit for me like it does with Tyranny.
I loved Pentiment, too, but I just wouldn't really compare it to New Vegas tbh. Tyranny has the whole element of building a coalition of factions and multiple endings thing going for it that makes it feel New-Vegasey to me. The comparison is probably a bit of a stretch, but it makes sense to me at least lol.
FNV is built on the chassis of a game with awful mechanics. It's actual strong point is the narrative. FNV might as well have been a point-and-click adventure, I'd argue.
Similarly, Avowed will have similar mechanics to Skyrim, FNV, Outer Worlds, etc. In terms of gameplay, it will be the same Bethesda slop. The question is whether or not it will have the narrative to make it stand out.