No, because it only selects the shown ones, so you can only delete like 45 at a time. At least that's how it works on the website, and it's ridiculous.
Mark as Read in the notification panel. How the hell is that still not an option? I've been asking for this over a decade since quick reply options became a thing (jellybean?). Options are still only Archive or Delete.
It still lags in productivity compared to a desktop app. For how much time we spend in email, I am surprised Outlook and Thunderbird still feel like they were built 20 years ago. Email clients get no love.