This is layer 2 or 3. It will be covered by the next few layers but I feel like it shouldn't be this fugly. I'm using Cura's Standard Quality except for temp which is set to 205. The filament is Inland PLA.
I second z offset. Weird that this happens only at a certain regular "column". Could be hiding an underextruded strand on the level below. In that case your temp might not be stable.
It's primarily written for klipper, but I've been been getting pretty good results dialing in my was-an-ender with Ellis' tuning guide (all but eliminated my problems with elephants foot). It goes over exactly what a good first layer should look and feel like, plus extra related settings.