But it all makes like a weird amount of sense. I mean Mario also isn't made of weird pixelated legos, either. It's like the writers were shown some stills from the game and told the basic story and then dropped acid.
We know that SMB3 was a play but we don't know that the other games in the series weren't. The 1993 movie might be the only truly canon entry in the franchise.
Funny enough, I don't think Wario and Waluigi are ever said to be siblings. Waluigi just kinda... showed up to a tennis match one day and then stuck around.
Edit: Out of curiosity, if you're downvoting me, are you downvoting because you disagree, or because the person meant it to be a joke? In the former case, it's both common sense and also Miyamoto said as much. In the latter case, there's no indication whatsoever that it's a joke, so would I have been wrong to "miss the joke"?