That's some pretty blatant cherry picking, but I'm sure it's to emphasize the humor of the source video.
Putting that aside, I've never been a fan of the Genesis sound chip. It's way too harsh and buzzy for my poor ears. I respect the opinion of people who love it, but I feel for the parents who had to tolerate hearing that every day.
Of course I was no better about not being annoying, especially when I would literally run around in circles while the end-of-stage music for Yoshi's Island played on a loop.
It was great for making buzzy electric guitar sounds in EXTREME games and that's about it. SNES sound chip was superior and probably capable of replicating the Genesis sound if they'd tried