Personalized mRNA vaccines for melanoma and lung cancer

www.optimistdaily.com A personalized mRNA Vaccine provides ‘real hope’ for melanoma patients | The Optimist Daily

Redefining cancer therapy: a closer look at the cutting-edge mRNA vaccine trials for melanoma.

I missed this before, but apparently we're now nearly a year into Merck and Moderna's Phase-3 trials of a novel mRNA vaccine (mRNA-4157) in combination with Keytruda to slow or halt aggressive melanoma growth. (press release), and about 4 months into a similar Phase 3 trial of the same drug combo for small cell lung cancer (press release). Here's hoping that 2025 is the year we cure (some kinds of) cancer!

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will_a113 @lemmy.ml

1mo ago

Personalized mRNA vaccines for melanoma and lung cancer

www.optimistdaily.com /2025/01/a-personalized-mrna-vaccine-provides-real-hope-for-melanoma-patients

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Conspiracy theorists in 2019: "Big Pharma is hiding the cure to cancer because they'd rather keep people on chemo"
Conspiracy theorists in 2025: "The vaccine for cancer is actually worse than cancer"
- The difference this time is that this won't be paid by the government like covid vaccine and in fact will be very expensive (i.e. how much people are willing to pay to cure their cancer?)
  How can you create such conspiracy, when they don't even want to give that vaccine?
  I suspect if we were forced to pay $500 or more to get covid vaccine we wouldn't have conspiracies either.
  
  The difference this time is that this won't be paid by the government like covid vaccine and in fact will be very expensive (i.e. how much people are willing to pay to cure their cancer?)
  In the USA.
  
  how much people are willing to pay to cure their cancer?)
  People are typically willing to pay everything they have to avoid dying and excruciating death.
  
  Somewhere between the answer to the following two questions.
  How much is your life worth to you?
  And
  How much is your life worth to your community.
  
  Could be, but to some people, vaccine is just a dirty word

US finally catching up with Cuba on cancer vaccines. Hopefully it'll be widely available.

the original article (linked in this article; from The Guardian) is over 8 months old.
- Yup. I linked both the original press release about melanoma as well as the one from October about the similar trial for lung cancer.

There are people in hospital, on the cusp of death, who will refuse to receive blood because it’s unknown whether it’s “vaccinated” mRNA blood or not.
I’m curious to see how this goes.
- That's their decision to make. I don't see the relevance to this discovery though. If those people don't want it, then that's their choice. Give it to people who do.
  
  There’s no differentiation in blood donations. Surgery consent is wrapped around blood consent so it may mean surgery is off the table as well, depending.
  Ofc it’s a choice, refusal of medical care is almost always on the table, unless you’re chaptered or deemed nondecisional or some such. As this tech becomes more mainstream, I’m curious to see how many bow out of medical cares going forward. Or, if this we be re-written as somehow different than the vaccine tech and therefore deemed ok because everyone wants a cure for cancer.
- I feel like most people will have a change of heart when they are actively dying in the hospital. Same as how many anti-abortion folks end up getting abortions when it’s their body on the line.
  
  Exactly. That’s my thought.
  Cure for cancer: yes. Support of this thing that made my god emperor look bad: no, on pain of my own death. Alternatively, support of this thing that made me extremely uncomfortable and robbed me of some life choices: no, even if it kills me. I will twist it around so theyre somehow not the same tech.
  Granted, there’s always the flat earther, dinosaurs bones are trolling fakes, chem trails, and the moon landing was another troll on all of humanity types. They’re probably all in on the Bill Gates cares enough about you to track you via nanites in the vaccine. I mean, why not? If you believe any of the other is the vaccine hype all that big of a stretch from there?
  Actual risk? Someone lives on the tippy tails of the bell curve, or there wouldn’t be a bell curve. There’s no such thing as a 100% with people, or medical care outcomes. Except eventual death. (I’m subtracting taxes because sovereign citizens really do try their best on that one.)
  All of that said, people are at deaths door a lot in hospital and will still refuse life saving care.
  Amputating gangrene is one. Not taking lactulose. Not taking diuretics. Guzzling sugar with diabetes. Having a hemoglobin of 5 and continuing to refuse blood that might be from a COVID vaccinated person. So why not refuse this too?
- Natural selection at its finest.

16 comments