They're referring to the fact that pretty much everyone in the comments defended why we still use QWERTY over any different keyboard.
Usually when people say "Big ____" they're referring to giant corportations pushing their agendas for profit against the wellbeing or benefit of society. In this instance, it's certainly being used in a tongue-in-cheek manner.
They're joking essentially that people who vehemently defend qwerty are perhaps a little brainwashed.
It is known that there are keyboard layouts which are more efficient and faster (qwerty came about as a means of preventing typewriter arms from hitting each other), but none have become mainstream because everyone's used to qwerty.
Even the Linux nerds who customize everything about their computer are probably still using the QWERTY keyboard layout. I've seen a lot of "arch btw" but never seen "dvorak btw".
The problem with Dvorak is that it’s English specific. It effectively hampers typing in non Germanic languages. And I’m not about to be switching layouts every time I switch input locales.
I'm an Arch user and I did try Dvorak for a few weeks. I eventually gave up because it was a huge hassle switching back and forth, remapping game controls, remapping code editor key combos, and so many other remaps. It just wasn't worth the effort.
I'd say it's got less to do with making money off the status quo, and more to do with lack of money in any of the alternatives. Most people can't type fast enough for extra layout efficiency to matter, and even fewer people care.
I did try switching, but gradually I also unlearned how to use QWERTY. If only we lived in a world with no hardcoded keyboard layouts...
For 5% improvement it's just not worth it for most people.
There are so many things pointing towards ditching QWERTY - WFH jobs, mobile devices, portable keyboards, even virtual projected keyboards rather than physical ones.
On the other hand, laptops are a bottleneck - even if nobody else uses your personal one but you, they still have to make one with a nonstandard layout (will e.g. Apple ever do that?) - and just bc newer, younger people learning how to use computers for the first time could choose a different layout, doesn't mean that many will (I mean at the mainstream level).
you can install the Colemak layout in software with one click. Works on Linux, Mac, and Windows. https://colemak.com/ I think if another, better layout catches on it could eventually be printed on devices